Quercetin Health Benefits

Quercetin’s best known mechanism of action involves its ability to stabilize mast cell membranes, which in turns can decrease the release of histamine. In this way it provides nutritional support for individuals who occasionally suffer from allergies. Other benefits include its cardiovascular support and protection of the gastrointestinal tract. A number of quercetin’s beneficial effects appear to be due to its antioxidant activity. Quercetin can scavenge free radicals and inhibit the oxidation of LDL cholesterol. By itself, and when paired with vitamin C, quercetin can reduce the incidence of oxidative damage to skin and nerves caused by glutathione depletion. This exclusive Thorne formula features quercetin phytosome bound to sunflower-sourced phospholipids to enhance its absorption.

Quercetin Phytosome Details

Quercetin is a type of plant compound called a flavonoid (a fancy name for a plant pigment) that contributes to the natural, vibrant colors of fruits and vegetables like apples, onions, berries, and tea. Flavonoids function as antioxidants, seeking out damaging free radicals and neutralizing them.*

Free radicals are caused by the daily oxidative stress placed on our bodies, and they are linked to cellular damage, accelerated aging, and chronic health conditions. 

Thorne’s Quercetin Phytosome offers the antioxidant benefits of a flavonoid, as well as its immune-supporting properties and the ability to support a healthy inflammatory response, which provides a range of health-promoting benefits.* 

As a natural compound, quercetin is typically characterized by poor absorption into the bloodstream, which is why the quercetin used in Thorne products is provided as a quercetin phytosome. A quercetin phytosome complex enhances the benefits of quercetin by utilizing phytosome technology to optimize the nutrient’s bioavailability. Thorne’s Quercetin Phytosome is up to 20 times more bioavailable than quercetin extract alone, for maximum benefit from a smaller amount.*

The image below shows graphically the comparison in bioavailability of Quercetin vs Quercetin Phytosome

Who can benefit from Quercetin Phytosome

• Anyone looking to support healthy immune function*

• Individuals seeking support from the effects of seasonal allergies or hives*

• Those looking to promote recovery and a healthy inflammatory response in the respiratory tract*

• Biohackers looking to optimize sirtuin function and decrease senescent cells*

• Anyone wanting to support a healthy aging process*

Immune and Allergy Support

Quercetin Phytosome offers a range of benefits for immune health – from general immune support, to nutritional support for seasonal allergy sufferers, to maintenance of a healthy respiratory tract.* Quercetin plays a crucial role in moderating immune function through several different actions, such as:  

• Supporting various types of immune cells that are necessary for an optimized immune response*

• Benefiting allergy sufferers by helping to regulate histamine release*

• Helping to support a normal inflammatory response, particularly in the respiratory tract*

 Unique Benefits for Healthy Aging

Cutting-edge research is placing quercetin in the spotlight for healthy aging because of new research that shows quercetin helps reduce cellular senescence.* Senescent cells are malfunctioning cells that have stopped dividing but do not die and remain in the body. Environmental factors, along with regular aging, causes a buildup of senescent cells, which can be associated with biological aging and age-related disorders.
 What makes Quercetin Phytosome a healthy aging superstar:

• Quercetin is one of only two nutrients that have been studied to reduce cellular senescence*

• Quercetin up-regulates sirtuins (key regulators of cellular health) associated with improved weight-related metabolic factors at the cellular level*

• The trio of antioxidant, sirtuin, and senescence support helps optimize healthy cellular aging*

Quercetin and its Anti-Covid Properties

Quercetin's potential efficacy in treating COVID-19 has been studied in recent case-control clinical studies. Quercetin has been found to have a multifactor beneficial action against SARS-CoV-2, which could help to counterbalance the effects of COVID-19 infection which is nicely summarised in the below diagram. For a review of the studies on quercetin for COVID-19 refer to the blog post Quercetin - benefits & what is the best absorbed form?

Warnings

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health professional before using this product.
INTERACTIONS
There are no known adverse interactions or contraindications at publication date.

Vitamin supplements should not replace a balanced diet. Always read the label. Use as directed. If symptoms persist, talk to your health professional. If you are pregnant or breastfeeding talk to your health professional.

*These statements have not been evaluated by the Food & Drug Administration or TGA. These products are not intended to diagnose, treat, cure or prevent any disease. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship.

References:

A. Riva, M. Ronchi, G. Petrangolini, S. Bosisio, P. Allegrini, Eur. J. Drug Metab. Pharmacokinet. 44 (2019) 169–177.

Rondanelli, M., Perna, S., Gasparri, C., Petrangolini, G., Allegrini, P., Cavioni, A., Faliva, M., Mansueto, F., Patelli, Z., Peroni, G., Tartara, A. and Riva, A., 2022. Promising Effects of 3-Month Period of Quercetin Phytosome® Supplementation in the Prevention of Symptomatic COVID-19 Disease in Healthcare Workers: A Pilot Study. Life, 12(1), p.66.